Medical marijuana in Missouri was legalized in November of 2018 with Amendment 2. While dispensaries are not operational yet, they are expected to be open mid-2020. Amendment 2 establishes a system of taxation and regulation for cannabis sales, and allows patients to cultivate their own cannabis (with additional licensing).

Missouri has granted 192 licenses for medical dispensaries, which is the minimum allowed under the state’s rules. In addition to THC preparations, the state previously passed a limited medical cannabis bill in 2014, House Bill 2238, which legalized the use of hemp and CBD derivatives for medical use. Cannabis for recreational purposes remains illegal in the state of Missouri.