What does it take to make a plain truly great? Southwest Oklahoma has an answer to your questions. Golden prairies and majestic mountains welcome you to the West in true iconic fashion.

Oklahoma’s Great Plains once housed a seizeable stretch of pure Americana known as Route 66, and regions still pays tribute to the highway of yesteryear with not not one, but two museums: the Oklahoma Route 66 Museum and the National Route 66 Museum. Whether you’re headed on the highway, looking for adventure or seeking wide open spaces, find where to buy cannabis in Southwest Oklahoma and head out on the plains.

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Map Legend

Alice's Restaurant Dispensary

312 E Eads Ave
Weatherford, OK 73096
Phone: (888) 328-7448
  • Medicinal
Store Profile

Big Chief Collective

1811 W Gore Blvd
Lawton, OK 73507
Phone: (580) 370-7193
  • Medicinal
Website Store Profile

Bud Hut MD

910 SW F Ave
Lawton, OK 73501
Phone: (580) 713-5002
  • Medicinal
Website Store Profile

Bullseye Natural Remedies

3090 Old 66 Rd
Hydro, OK 73048
Phone: (405) 663-9333
  • Medicinal
Website Store Profile

Cannabis Cafe

112 S Sheb Wooley Ave
Erick, OK 73645
Phone: (580) 526-2232
  • Medicinal
Store Profile

Cannawise

17 N Hwy 81
Duncan, OK 73533
Phone: (580) 606-0740
  • Medicinal
Website Store Profile

Critical Hit

1901 NW Cache Rd
Lawton, OK 73507
Phone: (580) 919-7994
  • Medicinal
Website Store Profile

Doctors Dispensary

1317 NW Sheridan Rd
Lawton, OK 73505
Phone: (580) 771-2009
  • Medicinal
Website Store Profile

Dub Dispensary

4200 Carriage Way
Weatherford, OK 73096
Phone: (580) 774-2214
  • Medicinal
Website Store Profile

Eden Cannabis Dispensary - Hobart

221 W 3rd St
Hobart, OK 73651
Phone: (580) 530-9878
  • Medicinal
Website Store Profile

Fluffys Apothecary

4313 NW Cache Rd
Lawton, OK 73505
Phone: (580) 699-2230
  • Medicinal
Website Store Profile

Green Healer

102 Falcon Rd
Elk City, OK 73644
Phone: (580) 821-2462
  • Medicinal
Store Profile

Happy Root 420 - Lawton

3130 NW Cache Rd
Lawton, OK 73505
Phone: (580) 699-3322
  • Medicinal
Website Store Profile

Herbal Care Center

2506 SW Lee Blvd
Lawton, OK 73505
Phone: (580) 678-1676
  • Medicinal
Website Store Profile

Hobart Garden Royale

325 S Main St
Hobart, OK 73651
Phone: (580) 682-4044
  • Medicinal
Website Store Profile

Kiowa Wellness Center

2000 N Main
Altus, OK 73521
Phone: (580) 379-9244
  • Medicinal
Website Store Profile

Lotus Gold - Duncan

424 S Hwy 81
Duncan, OK 73533
Phone: (580) 447-5181 ext. 224
  • Medicinal
Website Store Profile

Lotus Gold - Lawton

1908 NW Cache Rd
Lawton, OK 73507
Phone: (833) 422-3758 ext. 08
  • Medicinal
Website Store Profile

Main Street Wellness

107 W Main St
Sayre, OK 73662
Phone: (580) 799-0617
  • Medicinal
Website Store Profile

Med Dispensary

1925 W Gore Blvd
Lawton, OK 73501
Phone: (580) 699-5544
  • Medicinal
Website Store Profile

Med Shed

678 B St
Arapaho, OK 73620
Phone: (580) 789-4636
  • Medicinal
Website Store Profile

Medical Farm-A-Seed

3140 NW Cache Rd
Lawton, OK 73505
Phone: (580) 699-3323
  • Medicinal
Website Store Profile

Mister Mary Jane

328 S US-81
Duncan, OK 73533
Phone: (580) 786-2076
  • Medicinal
Website Store Profile

Mystic Leaf

901 E Broadway St Ste B
Altus, OK 73521
Phone: (580) 379-0222
  • Medicinal
Store Profile

Oklahoma Native Roots

12 S 4th St
Duncan, OK 73533
Phone: (580) 786-0711
  • Medicinal
Website Store Profile

Peace Pipe Bros

109 S 1st St
Anadarko, OK 73005
Phone: (405) 414-6922
  • Medicinal
Website Store Profile

Prohibition

115 W Rainey Ave
Weatherford, OK 73096
Phone: (580) 302-8506
  • Medicinal
Website Store Profile

Queen Crown Cannabis

1812 NW Fort Sill Blvd
Lawton, OK 73507
Phone: (580) 699-2255
  • Medicinal
Website Store Profile

Red Bud Dispensary

1502 N Broadway St
Marlow, OK 73055
Phone: (580) 658-9305
  • Medicinal
Website Store Profile

Re-Leaf Resolution

1021 E Davis Ave
Weatherford, OK 73096
Phone: (580) 890-8086
  • Medicinal
Store Profile

ReLeaf Wellness Center - Altus

400 E Broadway St
Altus, OK 73521
Phone: (580) 482-1259
  • Medicinal
Website Store Profile

RT66 Apothecary

2026 County St 2470 Ste 2
Hydro, OK 73048
Phone: (405) 663-1454
  • Medicinal
Website Store Profile

Starbuds - Lawton

2629 NW Cache Rd
Lawton, OK 73505
Phone: (580) 699-2833
  • Medicinal
Website Store Profile

Sugar Shack Dispensary

2502 NW Cache Rd Ste B
Lawton, OK 73505
Phone: (580) 699-7422
  • Medicinal
Website Store Profile

The Bud Ranch

1128 NW Cache Rd
Lawton, OK 73507
Phone: (580) 699-2027
  • Medicinal
Website Store Profile

The Peak - Cache

1706 NW Cache Rd
Lawton, OK 73507
Phone: (580) 235-9640
  • Medicinal
Website Store Profile

Therapeutic Herbal Centers

220 S Pennsylvania Ave
Mangum, OK 73554
Phone: (580) 379-2551
  • Medicinal
Website Store Profile

Tumbleweed's

415 SW 11th St
Lawton, OK 73501
Phone: (580) 699-2234
  • Medicinal
Website Store Profile

Twisted Leaf Dispensary

2610 SW Lee Blvd
Lawton, OK 73505
Phone: (580) 699-3684
  • Medicinal
Store Profile
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